Outstanding scientists
School of Blood and Bone Marrow Cryopreservation
Founded by Corresponding Member of the National Academy of Sciences of Ukraine
Mykola S. Pushkar
Mykola S. Pushkar is the founder of the Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine. Under his leadership, methods for preserving bone marrow, thyroid tissue, blood components and their application in treatment were developed. The Institute was created based on several divisions, including the Problem Laboratory of Low-Temperature Preservation of Bone Marrow and Blood, which was headed by Prof. Mykola S. Pushkar. He is a laureate of the USSR State Prize and the one of the A.A. Bogomolets Academy of Sciences Prize. Awarded the Order of the Red Banner of Labor and the Order of the Badge of Honor. He authored over 300 scientific works, including 9 monographs, 41 patents for inventions. Under his supervision 38 candidate dissertations were defended.
School of Reproductive System Cryobiology
Founded by the Academician of the NAS of Ukraine
Valentyn I. Grischenko
Thanks to Valentyn I. Grischenko, who headed the Institute in 1983-2011, this area has achieved significant success. A team of scientists under his leadership successfully performed in vitro fertilization of an oocyte for the first time in Ukraine (1984), which resulted in the birth of the first child in Ukraine “from a test tube” in 1991. The School has developed effective methods of cryopreservation of sperm, embryos and investigated ways to increase their fertility. Valentyn I. Grischenko is an Honored Worker of Science and Technology of Ukraine, laureate of the State Prizes of the USSR, the Ukrainian SSR and Ukraine, laureate of the A.A. Bogomolets Prize of the Academy of Sciences, the V.F. Snegirev Prize of the USSR Academy of Sciences. For his contribution to the development of cryobiology in 2010, the Society for Cryobiology awarded him the Basile Luyet medal and the Cryofellow title. Also he was bestowed with the “Badge of Honor”, “For Distinction” of the 3rd degree, the jubilee medal “For Valiant Labor”, the gold medal of the Polish Academy of Medical Sciences. He authored over 800 scientific works, including 21 monographs, 8 textbooks, 129 patents. Under the leadership of V. Grischenko, 33 doctors and 136 candidates of medical and biological sciences were trained. In his honour, an annual competition for the best scientific work among employees of the Institute for Problems of Cryobiology and Cryomedicine of the NAS of Ukraine was established.
School of Cryobiochemistry
Founded by the Corresponding Member of the National Academy of Sciences of Ukraine
Apollon M. Bilous
Corresponding Member of the National Academy of Sciences of Ukraine, Prof. Apollon M. Bilous was one of the organizers of the Institute and headed the Department of Cryobiochemistry. His studies of structure and functions of cells at low temperatures enabled the establishing of the mechanisms and patterns of cryodamage and improving the cryopreservation technologies. Apollon M. Bilous is a laureate of the State Prize of the Ukrainian SSR, a laureate of the A.A. Bogomolets Academy of Sciences Prize, a laureate of the Oleksander Palladin of the Academy of Sciences of the Ukrainian SSR Prize. He was awarded the Honorary Diploma of the Presidium of the Verkhovna Rada of the Ukrainian SSR. A. Bilous was the author of over 300 scientific works, including 15 monographs and 18 inventions. Under the guidance of A. Bilous, more than 30 candidate and 8 doctoral theses were defended. An annual competition for young scientists was founded in his honor.
School of Cryoimmunology
Founded by the Academician of the National Academy of Sciences of Ukraine Anatoliy M. Goltsev
Academician Anatoliy M. Goltsev, a student of Alla O. Tsutsayeva and Valentyn I. Grischenko, heads this direction. The school studies the immunological and pathophysiological foundations and mechanisms of development of oncology and autoimmune diseases to improve methods of their treatment with cryopreserved cells of various origins. Technologies for cryopreservation of bioobjects for immunotherapy of various pathologies have been developed. The possibilities of using cryopreserved products of the fetoplacental complex for the treatment of diseases of autoimmune genesis have been substantiated. Approaches to the diagnosis and treatment of malignant tumors using nanotechnology and ultralow temperatures have been developed. Anatoliy M. Goltsev is a laureate of the State Prize of Ukraine, a laureate of the V.P. Komisarenko Prize of the National Academy of Sciences of Ukraine, and an Honored Worker of Science and Technology of Ukraine. Anatoliy M. Goltsev has trained 22 candidates and 4 doctors of sciences. He is actively engaged in pedagogical activities. He heads the UNESCO Chair in Cryobiology at the IPCC of the National Academy of Sciences of Ukraine. A. Goltsev is the author of over 1,200 scientific works, particularly he co-authors 13 monographs and 58 inventions.
School of Theoretical Cryobiology
Founded by the Corresponding Member of the National Academy of Sciences of Ukraine
Yevhen O. Gordiyenko
This school, currently headed by Prof. Olga I. Gordienko, focuses on theoretical analysis and experimental study of the mechanisms of cryodamage and cryoprotection of cells. Physical and mathematical models as well as experimental methods are being developed to determine the characteristics of cell membranes and optimize cryopreservation regimens. The results of Yevgen O. Gordiyenko’s research were presented in more than 180 scientific papers, including 3 monographs, 11 patents. Under his leadership, 10 candidate and 4 doctoral dissertations were completed and successfully defended.
School of Cryoendocrinology
Founded by the Corresponding Member of the Academy of Sciences of the Ukrainian SSR
Aaron M. Utevsky
Aaron M. Utevsky initiated the study of the influence of hormones on metabolism, in particular the biochemistry of catecholamines (adrenaline, noradrenaline), and determined the nature and function of their metabolites, developed new methods for their research. He was the founder of research into the influence of low temperatures on the state of endocrine tissues, the developer of the method of cryopreservation of thyroid gland sections. Aaron Utevsky is an Honored Scientist, laureate of the Oleksandr Palladin Prize of the Academy of Sciences of Ukraine. A. Utevsky has prepared 65 candidates and 21 doctors of science. He was the author of over 250 scientific works, including monographs, textbooks, patents and copyright certificates.
School of Stem Cell Cryobiology and Tissue Engineering
Founded by Prof., Laureate of the State Prize of Ukraine
Oleksandr Yu. Petrenko (student of Apollon Bilous)
Under his leadership, significant progress was achieved in the study of proliferative and differentiation potential of stem cells when cultivated in three-dimensional scaffolds (alginate microspheres, gels and macroporous matrices of various natures), in identifying new approaches to cryopreservation of stem cells in suspension and as part of tissue engineering constructs. A significant contribution was made to the study of the therapeutic efficiency of hematopoietic and mesenchymal stem cells in experimental transplantation. A new approach to hypothermic storage of organs for transplantation involving paracrine factors of stem cells was identified. The results are presented in more than 500 publications, about 50 of which are published in journals of the first two quartiles (Q1 and Q2), which are most often cited. Oleksandr Yu. Petrenko has trained more than 20 candidates of science and doctors of philosophy. He is actively involved in teaching and managing international scientific projects.
